Betatrophin Levels were Increased in Pregnant Women with or without Gestational Diabetes Mellitus and Associated with Beta Cell Function Níveis de betatrofina aumentados em grávidas com ou sem diabetes mellitus gestacional e associados à função das células beta
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P-167: Association between Pregnancy Dietary Iron Intake and Gestational Diabetes Mellitus
Background: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications affecting approximately 7% of all pregnancies and up to 14% of pregnancies in high-risk populations. Although, dietary iron intake is one of preventive factors for Iron deficiency which leads to less preterm delivery, prematurity, and SGA but iron is a strong pro-oxidant and high body iron levels c...
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Background: Diabetes mellitus (DM) is a group of metabolic disorders such as DM I, DM II, secondary causes of DM and gestational diabetes mellitus characterized by hyperglycemic phonotype. The etiology of gestational diabetes mellitus is unknown. Recent studies address the chronic activity of immune system against infections (not autoimmunity) as an important cause of gestational diabetes melli...
متن کاملCirculating Betatrophin Is Strongly Increased in Pregnancy and Gestational Diabetes Mellitus
AIMS/HYPOTHESIS Betatrophin has recently been introduced as a novel hormone and promotor of beta cell proliferation and improved glucose tolerance in mouse models of insulin resistance. In obese and diabetic humans altered levels were reported and a role in pathophysiology of metabolic diseases was therefore hypothesized. However its release and regulation in women with gestational diabetes mel...
متن کاملIncreased Cord Blood Betatrophin Levels in the Offspring of Mothers with Gestational Diabetes
AIM Exposing a fetus to hyperglycemia can increase the risk for later-life metabolic disorders. Betatrophin has been proposed as a key regulator of pancreatic beta cell proliferation and lipid regulation. Highly responsive to nutritional signals, serum betatrophin concentrations have been found to be altered by various physiological and pathological conditions. We hypothesized that betatrophin ...
متن کاملComparison of Fetal Echocardiography for Fetal Cardiac Structure in Women with Gestational Diabetes Mellitus and Normal Pregnancies
BackgroundIncreased metabolic rate of hyperglycemia in gestational diabetes causes macrosomia, which can also affect the fetal heart. The thickness of the walls of the heart and its function in women with gestational diabetes mellitus (GDM) can change over time before treatment. We aimed to evaluate fetal cardiac structure in terms of ventricular wall thickness and its function in women w...
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